The first example that I have found, is an advertisement for Certs mints. The commercial highlights the fact that Certs contain "Retsyn," a trademarked name for a mixture of copper gluconate, hydrogenated cottonseed oil, and flavoring. It is the copper gluconate in Retsyn which gives Certs its signature green flecks.
In the 1950s and 1960s, Crest toothpaste emphasized their fluoristan content. At first it used stannous fluoride, marketed as "Fluoristan" (this was also the original brand name it was sold under—it was later changed from "Fluoristan" to "Crest with Fluoristan").
(http://bvikkivintage.blogspot.com/2009/10/vintage-crest-ads-from-196-1964.html)
I also noticed the advertisement of specific fabric contents. I see ads in the present day for things like cotton and Lycra, but these don't seem as popular as vintage fabric ads. The following in a vintage ad for Orlon. The Dupont Corporation created the first acrylic fibers in 1941 and trademarked them under the name Orlon.
(http://www.what-the-frock.com/2011_12_01_archive.html)
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